CLINICAL VALIDATION OF AN ULTRA HIGH-THROUGHPUT SPIRAL MICROFLUIDICS FOR THE DETECTION AND ENRICHMENT OF VIABLE CIRCULATING TUMOR CELLS.

Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells.

BackgroundCirculating tumor cells (CTCs) are cancer cells that can be isolated via liquid biopsy from blood and can be phenotypically and genetically characterized to provide critical information for guiding cancer treatment.Current analysis of CTCs is hindered by the throughput, selectivity and specificity of devices or assays used in CTC detectio

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Associations between humiliation, shame, self-harm and suicidal behaviours among adolescents and young adults: A systematic review protocol.

BackgroundSuicide is the second leading cause of death among young people worldwide and remains a major public health concern.Research indicates that negative social contexts involving familial and peer relationships, have far-reaching influences on levels of suicidal behaviours in later life.Previous systematic reviews have focused on evaluating a

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Contents and technical requirements for overhaul of Ruhr pumps

With the extension of service period of Shanshan-Lanzhou Oil Pipeline, Ruhrp pumps needed overhauling, for which the guidance of specific technical requirements would be required.According to the structural characteristics of Ruhr pumps, the key points and basis of overhaul of each structure were analyzed.Based on the structural characteristics of

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Autologous stem-cell transplantation as consolidation of first-line chemotherapy in patients with peripheral T-cell lymphoma: a multicenter GELTAMO/FIL study

Peripheral T-cell lymphomas Cupping Bowl (PTCL) are a heterogeneous group of rare lymphoid malignancies that mostly have poor prognoses with currently available treatments.Upfront consolidation with autologous stem cell transplantation (ASCT) is frequently carried out, but its efficacy has never been investigated in randomized trials.We designed a

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Optimization of Base Location and Patrol Routes for Unmanned Aerial Vehicles in Border Intelligence, Surveillance, and Reconnaissance

The location-routing problem (LRP) of unmanned aerial vehicles (UAV) in border patrol for Intelligence, Animals Surveillance, and Reconnaissance is investigated, where the locations of UAV base stations and the UAV flying routes for visiting the targets in border area are jointly optimized.The capacity of the base station and the endurance of the U

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